Probiotics are non–pathogenic bacteria or other microorganisms that have antagonistic activity against pathogenic and conditionally pathogenic microorganisms, ensuring the restoration of normal microflora, performing other functions useful for the animal. In other words, probiotics are living non–pathogenic microorganisms (or agents containing them), which, when used in adequate quantities, restore microbiocenosis (normalize the intestinal microflora) and have a healing effect.
The concept of "probiotic" is relatively new. It is believed that Ferdinand Vergin first used it in 1954. He compared the harmful properties of antibiotics and beneficial properties of good bacteria, calling the latter "probiotic". This word is of Greek origin: pro – "for", bios – "life", i.e. "for life" or "creating life". Vergin defined probiotics as a mixed culture of bacteria. They have a beneficial effect on the body, which, by taking them, improves its microflora.
If we consider the concept of "probiotics" from the point of view of medicine, in 2002 an official consensus was reached on the definition of probiotics. The definition adopted by the World Health Organization (WHO) states: "Probiotics (also called bacteria or cultures) are living microorganisms that, when taken in sufficient quantities, have a positive effect on human health." Probiotics include microorganisms (lactic acid bacteria, bifidobacteria), which are normal inhabitants of the intestines of a healthy person. Taking into account the peculiarities of digestion in animals and taking into account the many works of microbiologists, as well as the results of their own in vitro studies, Bonaka LLC decided to create a microbiological complex containing the biomass of bacteria from the species Lactococcus, Lactobacillus, Bifidobacterium, Propionibacterium. These microorganisms are the normoflora of the intestine. Our goal was to produce a safe, non-toxic probiotic even in case of overdose and in cases of prolonged use.
On the other hand, the spore microflora belong to the so–called self-eliminating antagonists - bacteria that are non-specific inhabitants of the gastrointestinal tract. They are often aggressive and can lead to the suppression of typical representatives of the normal flora of the gastrointestinal tract, are quickly excreted from the body and are not always safe for animals and poultry.
It is believed that the spore microflora of the genus Bacillus belongs to probiotic microorganisms that have a wide range of antagonistic activity in relation to pathogenic and potentially pathogenic bacteria, whereas lactic acid microorganisms, along with probiotic activity, additionally have prebiotic activity, i.e. they have a stimulating effect on the growth and vital activity of beneficial microflora, showing the properties of synbiotics. Moreover, the recommended time for prescribing spore probiotics is strictly limited – no more than 3-5 days, subject to strict dosing of the feed additive.